Enzyme activities in the oral fluids of patients suffering from bulimia: a controlled clinical trial.
Identifieur interne : 000288 ( Main/Exploration ); précédent : 000287; suivant : 000289Enzyme activities in the oral fluids of patients suffering from bulimia: a controlled clinical trial.
Auteurs : N. Schlueter [Allemagne] ; C. Ganss ; S. Pötschke ; J. Klimek ; C. HannigSource :
- Caries research [ 1421-976X ] ; 2012.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Amylases (métabolisme), Analyse de variance (MeSH), Boulimie nerveuse (complications), Boulimie nerveuse (enzymologie), Collagenases (métabolisme), Concentration en ions d'hydrogène (MeSH), Débit sécrétoire (MeSH), Femelle (MeSH), Humains (MeSH), Lysozyme (métabolisme), Myeloperoxidase (métabolisme), Mâle (MeSH), Pepsine A (métabolisme), Peptide hydrolases (métabolisme), Protéolyse (MeSH), Salive (enzymologie), Statistique non paramétrique (MeSH), Substances tampon (MeSH), Trypsine (métabolisme), Vomissement (enzymologie), Érosion dentaire (enzymologie), Érosion dentaire (étiologie), Études cas-témoins (MeSH).
- MESH :
- enzymologie : Boulimie nerveuse, Salive, Vomissement, Érosion dentaire.
- métabolisme : Amylases, Boulimie nerveuse, Collagenases, Lysozyme, Myeloperoxidase, Pepsine A, Peptide hydrolases, Trypsine.
- étiologie : Érosion dentaire.
- Adulte, Analyse de variance, Concentration en ions d'hydrogène, Débit sécrétoire, Femelle, Humains, Mâle, Protéolyse, Statistique non paramétrique, Substances tampon, Études cas-témoins.
English descriptors
- KwdEn :
- Adult (MeSH), Amylases (metabolism), Analysis of Variance (MeSH), Buffers (MeSH), Bulimia Nervosa (complications), Bulimia Nervosa (enzymology), Case-Control Studies (MeSH), Collagenases (metabolism), Female (MeSH), Humans (MeSH), Hydrogen-Ion Concentration (MeSH), Male (MeSH), Muramidase (metabolism), Pepsin A (metabolism), Peptide Hydrolases (metabolism), Peroxidase (metabolism), Proteolysis (MeSH), Saliva (enzymology), Secretory Rate (MeSH), Statistics, Nonparametric (MeSH), Tooth Erosion (enzymology), Tooth Erosion (etiology), Trypsin (metabolism), Vomiting (enzymology).
- MESH :
- chemical , metabolism : Amylases, Collagenases, Muramidase, Pepsin A, Peptide Hydrolases, Peroxidase, Trypsin.
- complications : Bulimia Nervosa.
- enzymology : Bulimia Nervosa, Saliva, Tooth Erosion, Vomiting.
- etiology : Tooth Erosion.
- Adult, Analysis of Variance, Buffers, Case-Control Studies, Female, Humans, Hydrogen-Ion Concentration, Male, Proteolysis, Secretory Rate, Statistics, Nonparametric.
Abstract
Patients with bulimia nervosa are at high risk for dental erosion. However, not all bulimic patients suffer from erosion, irrespective of the severity of their eating disorder. It is often speculated that differences in the saliva are important, however, little is known about salivary parameters in bulimic patients, particularly directly after vomiting. The aim of the clinical trial was to compare different salivary parameters of subjects suffering from bulimia with those of healthy controls. Twenty-eight subjects participated (14 patients with bulimia nervosa, 7 of them with erosion; 14 matched healthy controls). Resting and stimulated saliva of all participants was analysed as well as saliva collected from bulimic patients directly and 30 min after vomiting. Parameters under investigation were flow rate, pH, buffering capacity and the enzyme activities of proteases in general, collagenase, pepsin, trypsin, amylase, peroxidase, and lysozyme. Regarding flow rate, pH and buffering capacity only small differences were found between groups; buffering capacity directly after vomiting was significantly lower in bulimic subjects with erosion than in subjects without erosion. Differences in enzymatic activities were more pronounced. Activities of proteases, collagenase and pepsin in resting and proteases in stimulated saliva were significantly higher in bulimic participants with erosion than in controls. Peroxidase activity was significantly decreased by regular vomiting. Proteolytic enzymes seem to be relevant for the initiation and progression of dental erosion directly after vomiting, maybe by both hydrolysis of demineralized dentine structures as well as modulation of the pellicle layer.
DOI: 10.1159/000337105
PubMed: 22472533
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Enzyme activities in the oral fluids of patients suffering from bulimia: a controlled clinical trial.</title><author><name sortKey="Schlueter, N" sort="Schlueter, N" uniqKey="Schlueter N" first="N" last="Schlueter">N. Schlueter</name><affiliation wicri:level="1"><nlm:affiliation>Department of Conservative and Preventive Dentistry, Dental Clinic, Justus Liebig University, Giessen, Germany. nadine.schlueter@dentist.med.uni-giessen.de</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Conservative and Preventive Dentistry, Dental Clinic, Justus Liebig University, Giessen</wicri:regionArea><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion></affiliation></author><author><name sortKey="Ganss, C" sort="Ganss, C" uniqKey="Ganss C" first="C" last="Ganss">C. Ganss</name></author><author><name sortKey="Potschke, S" sort="Potschke, S" uniqKey="Potschke S" first="S" last="Pötschke">S. Pötschke</name></author><author><name sortKey="Klimek, J" sort="Klimek, J" uniqKey="Klimek J" first="J" last="Klimek">J. Klimek</name></author><author><name sortKey="Hannig, C" sort="Hannig, C" uniqKey="Hannig C" first="C" last="Hannig">C. Hannig</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="RBID">pubmed:22472533</idno><idno type="pmid">22472533</idno><idno type="doi">10.1159/000337105</idno><idno type="wicri:Area/Main/Corpus">000285</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000285</idno><idno type="wicri:Area/Main/Curation">000285</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000285</idno><idno type="wicri:Area/Main/Exploration">000285</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Enzyme activities in the oral fluids of patients suffering from bulimia: a controlled clinical trial.</title><author><name sortKey="Schlueter, N" sort="Schlueter, N" uniqKey="Schlueter N" first="N" last="Schlueter">N. Schlueter</name><affiliation wicri:level="1"><nlm:affiliation>Department of Conservative and Preventive Dentistry, Dental Clinic, Justus Liebig University, Giessen, Germany. nadine.schlueter@dentist.med.uni-giessen.de</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Conservative and Preventive Dentistry, Dental Clinic, Justus Liebig University, Giessen</wicri:regionArea><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion><wicri:noRegion>Giessen</wicri:noRegion></affiliation></author><author><name sortKey="Ganss, C" sort="Ganss, C" uniqKey="Ganss C" first="C" last="Ganss">C. Ganss</name></author><author><name sortKey="Potschke, S" sort="Potschke, S" uniqKey="Potschke S" first="S" last="Pötschke">S. Pötschke</name></author><author><name sortKey="Klimek, J" sort="Klimek, J" uniqKey="Klimek J" first="J" last="Klimek">J. Klimek</name></author><author><name sortKey="Hannig, C" sort="Hannig, C" uniqKey="Hannig C" first="C" last="Hannig">C. Hannig</name></author></analytic><series><title level="j">Caries research</title><idno type="eISSN">1421-976X</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Amylases (metabolism)</term><term>Analysis of Variance (MeSH)</term><term>Buffers (MeSH)</term><term>Bulimia Nervosa (complications)</term><term>Bulimia Nervosa (enzymology)</term><term>Case-Control Studies (MeSH)</term><term>Collagenases (metabolism)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Hydrogen-Ion Concentration (MeSH)</term><term>Male (MeSH)</term><term>Muramidase (metabolism)</term><term>Pepsin A (metabolism)</term><term>Peptide Hydrolases (metabolism)</term><term>Peroxidase (metabolism)</term><term>Proteolysis (MeSH)</term><term>Saliva (enzymology)</term><term>Secretory Rate (MeSH)</term><term>Statistics, Nonparametric (MeSH)</term><term>Tooth Erosion (enzymology)</term><term>Tooth Erosion (etiology)</term><term>Trypsin (metabolism)</term><term>Vomiting (enzymology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Amylases (métabolisme)</term><term>Analyse de variance (MeSH)</term><term>Boulimie nerveuse (complications)</term><term>Boulimie nerveuse (enzymologie)</term><term>Collagenases (métabolisme)</term><term>Concentration en ions d'hydrogène (MeSH)</term><term>Débit sécrétoire (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Lysozyme (métabolisme)</term><term>Myeloperoxidase (métabolisme)</term><term>Mâle (MeSH)</term><term>Pepsine A (métabolisme)</term><term>Peptide hydrolases (métabolisme)</term><term>Protéolyse (MeSH)</term><term>Salive (enzymologie)</term><term>Statistique non paramétrique (MeSH)</term><term>Substances tampon (MeSH)</term><term>Trypsine (métabolisme)</term><term>Vomissement (enzymologie)</term><term>Érosion dentaire (enzymologie)</term><term>Érosion dentaire (étiologie)</term><term>Études cas-témoins (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Amylases</term><term>Collagenases</term><term>Muramidase</term><term>Pepsin A</term><term>Peptide Hydrolases</term><term>Peroxidase</term><term>Trypsin</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Bulimia Nervosa</term></keywords><keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Boulimie nerveuse</term><term>Salive</term><term>Vomissement</term><term>Érosion dentaire</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Bulimia Nervosa</term><term>Saliva</term><term>Tooth Erosion</term><term>Vomiting</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Tooth Erosion</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Amylases</term><term>Boulimie nerveuse</term><term>Collagenases</term><term>Lysozyme</term><term>Myeloperoxidase</term><term>Pepsine A</term><term>Peptide hydrolases</term><term>Trypsine</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Érosion dentaire</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Analysis of Variance</term><term>Buffers</term><term>Case-Control Studies</term><term>Female</term><term>Humans</term><term>Hydrogen-Ion Concentration</term><term>Male</term><term>Proteolysis</term><term>Secretory Rate</term><term>Statistics, Nonparametric</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Analyse de variance</term><term>Concentration en ions d'hydrogène</term><term>Débit sécrétoire</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Protéolyse</term><term>Statistique non paramétrique</term><term>Substances tampon</term><term>Études cas-témoins</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Patients with bulimia nervosa are at high risk for dental erosion. However, not all bulimic patients suffer from erosion, irrespective of the severity of their eating disorder. It is often speculated that differences in the saliva are important, however, little is known about salivary parameters in bulimic patients, particularly directly after vomiting. The aim of the clinical trial was to compare different salivary parameters of subjects suffering from bulimia with those of healthy controls. Twenty-eight subjects participated (14 patients with bulimia nervosa, 7 of them with erosion; 14 matched healthy controls). Resting and stimulated saliva of all participants was analysed as well as saliva collected from bulimic patients directly and 30 min after vomiting. Parameters under investigation were flow rate, pH, buffering capacity and the enzyme activities of proteases in general, collagenase, pepsin, trypsin, amylase, peroxidase, and lysozyme. Regarding flow rate, pH and buffering capacity only small differences were found between groups; buffering capacity directly after vomiting was significantly lower in bulimic subjects with erosion than in subjects without erosion. Differences in enzymatic activities were more pronounced. Activities of proteases, collagenase and pepsin in resting and proteases in stimulated saliva were significantly higher in bulimic participants with erosion than in controls. Peroxidase activity was significantly decreased by regular vomiting. Proteolytic enzymes seem to be relevant for the initiation and progression of dental erosion directly after vomiting, maybe by both hydrolysis of demineralized dentine structures as well as modulation of the pellicle layer.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22472533</PMID><DateCompleted><Year>2012</Year><Month>10</Month><Day>09</Day></DateCompleted><DateRevised><Year>2012</Year><Month>04</Month><Day>27</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1421-976X</ISSN><JournalIssue CitedMedium="Internet"><Volume>46</Volume><Issue>2</Issue><PubDate><Year>2012</Year></PubDate></JournalIssue><Title>Caries research</Title><ISOAbbreviation>Caries Res</ISOAbbreviation></Journal><ArticleTitle>Enzyme activities in the oral fluids of patients suffering from bulimia: a controlled clinical trial.</ArticleTitle><Pagination><MedlinePgn>130-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1159/000337105</ELocationID><Abstract><AbstractText>Patients with bulimia nervosa are at high risk for dental erosion. However, not all bulimic patients suffer from erosion, irrespective of the severity of their eating disorder. It is often speculated that differences in the saliva are important, however, little is known about salivary parameters in bulimic patients, particularly directly after vomiting. The aim of the clinical trial was to compare different salivary parameters of subjects suffering from bulimia with those of healthy controls. Twenty-eight subjects participated (14 patients with bulimia nervosa, 7 of them with erosion; 14 matched healthy controls). Resting and stimulated saliva of all participants was analysed as well as saliva collected from bulimic patients directly and 30 min after vomiting. Parameters under investigation were flow rate, pH, buffering capacity and the enzyme activities of proteases in general, collagenase, pepsin, trypsin, amylase, peroxidase, and lysozyme. Regarding flow rate, pH and buffering capacity only small differences were found between groups; buffering capacity directly after vomiting was significantly lower in bulimic subjects with erosion than in subjects without erosion. Differences in enzymatic activities were more pronounced. Activities of proteases, collagenase and pepsin in resting and proteases in stimulated saliva were significantly higher in bulimic participants with erosion than in controls. Peroxidase activity was significantly decreased by regular vomiting. Proteolytic enzymes seem to be relevant for the initiation and progression of dental erosion directly after vomiting, maybe by both hydrolysis of demineralized dentine structures as well as modulation of the pellicle layer.</AbstractText><CopyrightInformation>Copyright © 2012 S. Karger AG, Basel.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Schlueter</LastName><ForeName>N</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Conservative and Preventive Dentistry, Dental Clinic, Justus Liebig University, Giessen, Germany. nadine.schlueter@dentist.med.uni-giessen.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ganss</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Pötschke</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Klimek</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Hannig</LastName><ForeName>C</ForeName><Initials>C</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2012</Year><Month>04</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Caries Res</MedlineTA><NlmUniqueID>0103374</NlmUniqueID><ISSNLinking>0008-6568</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002021">Buffers</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 1.11.1.7</RegistryNumber><NameOfSubstance UI="D009195">Peroxidase</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.2.1.-</RegistryNumber><NameOfSubstance UI="D000681">Amylases</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.2.1.17</RegistryNumber><NameOfSubstance UI="D009113">Muramidase</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.-</RegistryNumber><NameOfSubstance UI="D010447">Peptide Hydrolases</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.21.4</RegistryNumber><NameOfSubstance UI="D014357">Trypsin</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.23.1</RegistryNumber><NameOfSubstance UI="D010434">Pepsin A</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.24.-</RegistryNumber><NameOfSubstance UI="D017364">Collagenases</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000681" MajorTopicYN="N">Amylases</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000704" MajorTopicYN="N">Analysis of Variance</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002021" MajorTopicYN="N">Buffers</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D052018" MajorTopicYN="N">Bulimia Nervosa</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000201" MajorTopicYN="Y">enzymology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017364" MajorTopicYN="N">Collagenases</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006863" MajorTopicYN="N">Hydrogen-Ion Concentration</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009113" MajorTopicYN="N">Muramidase</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010434" MajorTopicYN="N">Pepsin A</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010447" MajorTopicYN="N">Peptide Hydrolases</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009195" MajorTopicYN="N">Peroxidase</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D059748" MajorTopicYN="N">Proteolysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000201" MajorTopicYN="Y">enzymology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012636" MajorTopicYN="N">Secretory Rate</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018709" MajorTopicYN="N">Statistics, Nonparametric</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014077" MajorTopicYN="N">Tooth Erosion</DescriptorName><QualifierName UI="Q000201" MajorTopicYN="Y">enzymology</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014357" MajorTopicYN="N">Trypsin</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014839" MajorTopicYN="N">Vomiting</DescriptorName><QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2011</Year><Month>08</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2012</Year><Month>01</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>4</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>4</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>10</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">22472533</ArticleId><ArticleId IdType="pii">000337105</ArticleId><ArticleId IdType="doi">10.1159/000337105</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country></list><tree><noCountry><name sortKey="Ganss, C" sort="Ganss, C" uniqKey="Ganss C" first="C" last="Ganss">C. Ganss</name><name sortKey="Hannig, C" sort="Hannig, C" uniqKey="Hannig C" first="C" last="Hannig">C. Hannig</name><name sortKey="Klimek, J" sort="Klimek, J" uniqKey="Klimek J" first="J" last="Klimek">J. Klimek</name><name sortKey="Potschke, S" sort="Potschke, S" uniqKey="Potschke S" first="S" last="Pötschke">S. Pötschke</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Schlueter, N" sort="Schlueter, N" uniqKey="Schlueter N" first="N" last="Schlueter">N. Schlueter</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SuicidDentistV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000288 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000288 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SuicidDentistV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:22472533
|texte= Enzyme activities in the oral fluids of patients suffering from bulimia: a controlled clinical trial.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:22472533" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SuicidDentistV1
| This area was generated with Dilib version V0.6.39. |  |